Originally, the medicine prescribed by the doctor was: take half glimepiride tablet 2mg / once a day, plus metformin hydrochloride tablet 0.25g, take two tablets / three times a day. When I went to renew the prescription, I said that one of them was out of stock, so I prescribed metformin glipizide capsule (metformin hydrochloride 250mg, glipizide 2.5mg) to take one capsule / twice a day. I would like to ask, is it better to take these two drugs alone, or to take this synthetic drug? I used to eat half of glipizide, but now I can't cut it in half and increase the amount. However, the amount of metformin hydrochloride decreased from three times a day to two times. If it's better to take the two alone, I'll go out and buy them myself. Since the hospital doesn't have them.
It is still recommended to take separate drugs. Although glimepiride and glipizide are the same kind of drugs, their hypoglycemic effects are still different, and blood glucose may fluctuate after changing hypoglycemic drugs. There are many manufacturers of glimepiride, and the price is low. It is recommended to continue to use glimepiride. The dose of fixed dose compound preparation cannot be adjusted at will, but it is more convenient to take.
Look at the blood glucose control, recheck the fasting blood glucose and the blood glucose after three meals. For the purpose of stable blood glucose and tolerable side effects, it is not easy to change the dose and dosage form. You can buy your own medicine, control excessive total calorie intake, persevere, exercise, strengthen your body and get more sun exposure
The combination of hypoglycemic drugs with different action principles can be made into compound preparations, which can reduce the number of times of taking drugs. If the dose is similar, you can change to compound preparation. Pay close attention to blood glucose after dressing change, including fasting blood glucose and postprandial blood glucose.