Type II renal tubular acidosis
It is characterized by hypofunction of reabsorption of sodium carbonate in proximal renal tubules, resulting in the decrease of this salt in blood, showing Hyperchloric acidosis. As the reabsorption of sodium carbonate in the proximal tubule decreases, the sodium carbonate reaching the distal renal tubule increases. If the absorption threshold of the latter is exceeded, the urinary sodium carbonate increases and the urinary pH increases; If the sodium carbonate in the blood drops to a certain extent and the renal tubules can completely absorb the sodium carbonate in the glomerular filtrate, the urine can return to acidity and the urine pH can decrease. In addition, the reabsorption of glucose, phosphate, uric acid and amino acids in the proximal renal tubules can also be decreased, which is characterized by Fanconi syndrome.
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