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Thyroid hormone resistance syndrome

Thyroid hormone resistance syndrome (srth), also known as thyroid hormone refractory syndrome or thyroid hormone insensitivity syndrome (this), was first reported by refetoff in 1967. The disease is mostly familial, and there are a few sporadic cases, accounting for about 1 / 3. Mostly in children and adolescents, the youngest is newborns, both men and women. Clinical manifestations: serum free T4 (FT4) and free T3 (FT3) increased continuously, while thyroid stimulating hormone (TSH) was normal. The patient had no effects of drugs, non thyroid diseases and abnormal thyroid hormone transport.

Symptoms

Hypothyroidism

Familial anti vitamin D rickets

Thyroglossal duct cyst and fistula

Mental disorders associated with hypothyroidism

Thyroid microcarcinoma

Hyperthyroidism with pregnancy

Hyperthyroid liver disease

Pseudohypoparathyroidism

Hyperthyroidism bone mineral disease

Nodular goiter

Menstrual fever

Mental disorders associated with thyroid dysfunction

Cystic lymphangioma of neck

Menstrual salivation

Goiter with normal thyroid function

Tuberculosis of cervical lymph nodes

Resting lymphocytic thyroiditis

Gigantism and acromegaly

Cytomegalovirus disease

Acute lymphocytic leukemia

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