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Thalassemia

Thalassemia is also known as marine anemia. It is a group of hereditary small cell hemolytic anemia. Its common feature is that one or more globin peptide chains in hemoglobin are reduced or unable to be synthesized due to the defect of globin gene. The clinical symptoms of this group of diseases are different, most of which are chronic progressive hemolytic anemia. The disease was first described by Cooley and Lee in 1925. It was first found in the Mediterranean region. At that time, it was called thalassemia and called marine anemia abroad. In fact, the disease spreads all over the world, especially in the Mediterranean, Central Africa, Asia and the South Pacific. In China, Guangdong, Guangxi, Guizhou and Sichuan are the most. If the husband and wife are the cause of homothalassemia, each pregnancy, their children have 1 / 4 chance of being normal, 1 / 2 chance of being the cause, and the other 1 / 4 chance of being patients with severe thalassemia.

Symptoms

Simple purpura

Erythema multiforme

cholecystitis

Biliary ascariasis

Polycystic ovary syndrome

Hyperhidrosis

Single atrium

Simple pulmonary eosinophilia

Single ventricle

Cholesterol pneumonia

Escherichia coli pneumonia

Spinal vascular malformation type II and III

Choking

Multiple system organ failure

Typical preexcitation syndrome

Building disease syndrome

Multiple pulmonary infection

Amyloid cardiomyopathy

Amyloidosis

Dansha

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