Streptococcus pneumoniae septicemia

Streptococcus pneumoniae sepsis can be secondary to Streptococcus pneumoniae pneumonia, otitis media, mastoiditis and pharyngitis. Most of the bacteria enter the blood through the thoracic duct through the drainage lymphatic route from the lung. In the case of otitis media and mastoiditis, Streptococcus pneumoniae can enter the blood through the venous sinus. Among the patients with Streptococcus pneumoniae pneumonia, the blood culture of some cases is positive, and the positive rate increases with age. Splenectomy is more common in patients, which may be related to the powerful phagocytosis and killing of capsulated Streptococcus pneumoniae by the spleen mononuclear phagocyte system. Patients with other original severe diseases (such as sickle cell anemia and low immune function) are prone to Streptococcus pneumoniae sepsis.