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Secondary sideroblastic anemia

Secondary sideroblastic anemia is caused by the inhibition of heme synthesis by a variety of drugs, poisons and some diseases. It is characterized by a large number of circular sideroblasts in the bone marrow, ineffective production of red blood cells, excessive tissue iron reserves and small cell hypochromic anemia in peripheral blood. The disease is divided into acquired and hereditary, as well as vitamin B6 reactive anemia. Acquired is divided into primary and secondary. Poor utilization of iron, disorder of heme synthesis and ineffective production of red blood cells are the main links of the disease. The pathogenesis of this disease is the lack of various enzymes and coenzymes related to heme synthesis, decreased activity and blocked activity.


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