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Secondary sideroblastic anemia

Secondary sideroblastic anemia is caused by the inhibition of heme synthesis by a variety of drugs, poisons and some diseases. It is characterized by a large number of circular sideroblasts in the bone marrow, ineffective production of red blood cells, excessive tissue iron reserves and small cell hypochromic anemia in peripheral blood. The disease is divided into acquired and hereditary, as well as vitamin B6 reactive anemia. Acquired is divided into primary and secondary. Poor utilization of iron, disorder of heme synthesis and ineffective production of red blood cells are the main links of the disease. The pathogenesis of this disease is the lack of various enzymes and coenzymes related to heme synthesis, decreased activity and blocked activity.

Symptoms

Methotrexate related lymphoproliferative diseases

Megaloblastic anemia

Secondary thrombocytosis

Anemia caused by hypothyroidism

Bacteremia

Echinocytosis secondary to severe liver disease

Plasma cell leukemia

Familial polycythemia

Zygomycosis

Progressive pigmented purpura dermatosis

Giant platelet disease

Macroglobulinemia

Giant cell arteritis scleritis

Acute suppurative tenosynovitis

Cervical spinal cord injury

Open neck injury

Accumulated stagnation

Intermittent exotropia

Viral hepatitis A

Acute abscess

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