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Secondary cutaneous follicular central cell lymphoma

According to the statistics of NCI, among 1175 cases of NHL, there are 392 cases of FCCL, accounting for 34%. In 1771 cases of NHL (1972-198), 115 cases (only 6.5%) were reported by Shanghai lymphoma cooperation group, which is rare and may be related to missed diagnosis. FCCL most often occurs in lymph nodes and can also occur outside nodes, such as spleen, gastrointestinal tract, bone marrow, tonsil and skin. It mainly occurs in the middle-aged and the elderly, and it is slightly more common in men. FCC4% secondary CML system. Mitotic cells were common in FCCL, 259 of 392 cases of NCI (68.2%). There were 55 cases (59.8%) in the Shanghai lymphoma cooperation group, followed by 22 cases (24%) of mixed cell, 10 cases (11%) of large split cell and 5 cases (5.4%) of non split cell. Although the large cell nature of FCCL is moderately malignant, it is generally low-grade malignant. The prognosis of schizocytic is good, and the 5-year survival rate is 70%. The 5-year survival rates of mixed cell and large cell were 50% and 45%, respectively. Subtypes of secondary cutaneous follicular central cell lymphoma. According to Burg statistics, central cell (CC), central blastic / central cell (CB / CC) and CB account for 8%, 3% ~ 6% and 2.5% ~ 4% of CML respectively. We have seen 18 cases, including 9 cases of CB / cc, 7 cases of CC and 2 cases of CB.


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