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Phenothiazine antipsychotic poisoning

Antipsychotics, i.e. strong sedatives, are mainly used to treat acute and chronic mental diseases. Phenothiazines include chlorpromazine (dongmianling, cola Jing, chlorpromazine), perphenazine (hydroxypiperazine, perphenazine, trilafon), thioridazine, etc. Phenothiazines have strong M-receptor affinity, obvious sedative and hypotensive effects, but less extrapyramidal reaction. Phenothiazines are the most common acute poisoning, causing cardiac and neurotoxicity, extrapyramidal reaction and anticholinergic symptoms, and less death. Phenothiazine has no specific antidote, and the rescue method is mainly symptomatic support treatment.


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