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Phenothiazine antipsychotic poisoning

Antipsychotics, i.e. strong sedatives, are mainly used to treat acute and chronic mental diseases. Phenothiazines include chlorpromazine (dongmianling, cola Jing, chlorpromazine), perphenazine (hydroxypiperazine, perphenazine, trilafon), thioridazine, etc. Phenothiazines have strong M-receptor affinity, obvious sedative and hypotensive effects, but less extrapyramidal reaction. Phenothiazines are the most common acute poisoning, causing cardiac and neurotoxicity, extrapyramidal reaction and anticholinergic symptoms, and less death. Phenothiazine has no specific antidote, and the rescue method is mainly symptomatic support treatment.

Symptoms

Radiation myelopathy

Wind cold headache

Radiation peripheral neuropathy

Wind heat headache

African trypanosomiasis

Rheumatic chorea

Recurrent aseptic meningitis

Accessory nerve injury

Paraneoplastic myelopathy

Generalized flat xanthoma

Radiation thyroiditis

Non thyroid morbid syndrome

Obese reproductive incompetence syndrome

Wind temperature

Female androgenic alopecia

Mixed Acid-Base Disturbances

Reactive plasmacytosis

Nonketotic hyperglycemia hyperosmolar coma

Mast cell leukemia

Pulmonary eosinophilic infiltration

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