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Myasthenia syndrome

Lambert Eaton myasthenic syndrome (lems) is a rare autoimmune disease involving presynaptic membrane voltage-gated Ca ion channel of nerve muscle connection, which affects the excitation contraction coupling process. The inhibition of voltage-gated Ca ion channel by the disease reduces the release of acetylcholine from presynaptic membrane, which affects the generation of end plate potential and the contraction process of muscle. Lems is similar to myasthenia gravis in etiology, but they have many differences in clinical manifestations and pathogenesis. The susceptible population of Lambert Eaton myasthenia syndrome is middle-aged and elderly patients, and adolescents are occasionally involved. Because of its relatively rare, there is no statistics on the incidence rate of this disease.

Symptoms

Amyotrophic lateral sclerosis

Myotonic myopathy

Tuberous sclerosis

Progressive muscular dystrophy

Progressive spinal muscular atrophy

Progressive bulbar paralysis

Acute enteritis

Acute pancreatitis

Alcoholic hepatitis

Acute gastritis

Alcoholic cirrhosis

Thyroid tumor

Hyperthyroidism exophthalmos

Hypoparathyroidism

Hyperparathyroidism

Gigantism

Interstitial pneumonia

Interstitial lung disease

Acute upper respiratory tract infection

Acute respiratory distress syndrome

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