Home > internal medicine > Multiple endocrine tumor syndrome type I

Multiple endocrine tumor syndrome type I

Multiple endocrine tumor syndrome (men): it is a hereditary tumor syndrome with autosomal dominant inheritance involving a variety of endocrine organs. Its clinical manifestations are diverse. Two or more endocrine glands have functional tumors at the same time or successively, resulting in corresponding hormone excess. It is divided into four types: MEN-1 type, MEN-2A type, MEN-2b type, MEN-1 and MEN-2 mixed type. MEN-1 type is characterized by multifocal endocrine tumors that mainly involve the parathyroid gland, endocrine pancreas, anterior pituitary, adrenal cortex, thymus and other endocrine tissues. Among them, adrenocortical diseases account for 20% ~ 40%, often bilateral proliferative and nonfunctional lesions.

Symptoms

Multiple fibrous dysplasia

Hirsutism

multiple glandular deficiency syndrome

Skin manifestations of DF-2 sepsis

Simple spinal tuberculosis

Monocytic leukemia

Geomycosis

Large granular lymphocytic leukemia

Hypocalcemia and hypomagnesemia

pure red cell aplasia

Dubo histoplasmosis

Simple pulmonary eosinophilic infiltration

Low proliferative acute leukemia

Digoorg syndrome

Mucopolysaccharide storage disease

Convex meningioma of brain

Choledocholithiasis

proteinuria

Type IV spinal vascular malformation

Bile reflux gastritis

Common Health Issues

Health News