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Multiple endocrine tumor syndrome type I

Multiple endocrine tumor syndrome (men): it is a hereditary tumor syndrome with autosomal dominant inheritance involving a variety of endocrine organs. Its clinical manifestations are diverse. Two or more endocrine glands have functional tumors at the same time or successively, resulting in corresponding hormone excess. It is divided into four types: MEN-1 type, MEN-2A type, MEN-2b type, MEN-1 and MEN-2 mixed type. MEN-1 type is characterized by multifocal endocrine tumors that mainly involve the parathyroid gland, endocrine pancreas, anterior pituitary, adrenal cortex, thymus and other endocrine tissues. Among them, adrenocortical diseases account for 20% ~ 40%, often bilateral proliferative and nonfunctional lesions.


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