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Monoclonal gammopathy with peripheral neuropathy

Monoclonal gammopathy with peripheral neuropathy, also known as paraalbuminemia peripheral neuropathy. When there is too much M protein in the blood, it is called monoclonal immunoglobulin disease, also known as immunoglobulin disease, accessory protein disease or plasma cell disease. The pathological significance of M protein in blood to peripheral nerve is that M protein contains one or more antibodies against myelin sheath or axon membrane, such as anti MAG, GM1 and GD1 antibodies. In idiopathic peripheral neuropathy of unknown cause, 10% were combined with monoclonal bingqiu disease, while 29% ~ 71% of monoclonal bingqiu disease (MGUS) of unknown significance were combined with peripheral neuropathy, suggesting that monoclonal bingqiu disease is related to peripheral neuropathy.


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