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Hypertonic dehydration

Hypertonic dehydration refers to the loss of water and sodium at the same time, but the lack of water is more than the lack of sodium, so the serum sodium is higher than the normal range, and the extracellular fluid is hypertonic, also known as primary water shortage. When water shortage is more than sodium deficiency, the osmotic pressure of extracellular fluid increases, the secretion of antidiuretic hormone increases, the reabsorption of water by renal tubules increases and the urine volume decreases. Aldosterone secretion increases and sodium and water reabsorption increases to maintain blood volume. If the water shortage continues, the osmotic pressure of extracellular fluid will further increase, and the intracellular fluid will move out of the cell. The degree of water shortage in the cell will exceed the degree of water shortage in the extracellular fluid, and finally lead to water shortage in brain cells, which will cause brain dysfunction.


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