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Gardner syndrome

Gardner syndrome, also known as Weiner Gardner syndrome, familial multiple colonic polyps osteoma soft tissue tumor syndrome and familial colonic polyps. It is a chromosomal dominant disease, which is a multifaceted manifestation of a single gene. In 1905, Gardner reported that patients with colonic polyposis complicated with familial osteoma, soft tissue tumor and colon cancer had more opportunities. Later, Smith proposed the triple syndrome of colonic polyposis, soft tissue tumor and osteoma as Gardner syndrome in 1958. The pathogenesis of this syndrome is unknown. Colonic polyps are adenomatous polyps, the canceration rate is 50%, and osteomas are benign. Both men and women have a family history.


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