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Focal segmental glomerulosclerosis

Focal segmental glomerulosclerosis (FSGS) is a common primary glomerular disease in children and adults with nephrotic syndrome (NS). Its histopathological feature is glomerular segmental scar with or without the formation and adhesion of foam cells in glomerular capillaries. Focal refers to that only part of the glomerulus is involved (affected glomerulus < 50%); Segmental refers to the involvement of some lobules of glomerulus; Glomerulosclerosis refers to the phased vitreous changes or scar formation of the whole glomerulus.


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