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Diabetic peripheral neuropathy in the elderly

Neuropathy is one of the most common complications of diabetes. Its prevalence rate can reach 7% to 50%. If it includes all kinds of subclinical neuropathy, it can reach as high as 90%. It is an important cause of diabetes patients' disability and death, and seriously threatens the health of diabetic patients. Any part of the nervous system (peripheral nerve, spinal cord and brain) can be involved, which can occur alone or in combination, among which peripheral neuropathy is the most common. Especially in the elderly peripheral neuropathy, diabetes is the most common cause. Peripheral neuropathy refers to the continuous disorder of spinal cord and brainstem motor neurons, primary sensory neurons, peripheral autonomic neurons, axons and supporting tissues, which can have a variety of clinical manifestations. Its neuropathology showed Schwann cell edema, axonal degeneration and segmental demyelination.


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