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Cryoglobulinemia and renal damage

Cryoglobulin refers to a kind of globulin that precipitates or gels when the plasma temperature drops to 4 ~ 20 ℃, and dissolves when the temperature rises to 37 ℃. Normal serum contains only a small amount of cryoglobulin. When its concentration exceeds 100mg / L, it is called cryoglobulinemia. Elevated serum cryoglobulin is often accompanied by glomerular lesions, which is called renal damage due to cryoglobulinemia.

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