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Cholestatic gangrene

Cholestatic jaundice refers to that bile acid and bilirubin in blood are higher than normal due to cholestasis. The so-called cholestasis is the slowing down or stagnation of bile flow caused by various harmful factors, such as dysfunction of hepatocyte excretion of bile, inhibition of bile secretion or intrahepatic and extrahepatic biliary obstruction. Cholestatic jaundice is mainly associated with increased direct bilirubin.



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